harpy.datasets.macsima_colorectal_carcinoma

harpy.datasets.macsima_colorectal_carcinoma(subset=True, path=None, **kwargs)

Load the Colorectal Carcinoma MACSima dataset as a spatialdata.SpatialData object.

This function provides access to a highly multiplexed MACSima imaging dataset of colorectal carcinoma tissue. By default, a standardized subset of the data is returned for convenience and faster loading (5-plex), but the full dataset (63-plex) can be loaded if desired (requires ~50 GB of storage).

Data downloaded from (accessed 20/11/2025): https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmiltenyibiotec.canto.de%2Fdirect%2Fother%2Fo1l6flt6e11bl87qbk04rf2m1g%2FtkD2iQTphD-7AfwFfttGdlvvLmw%2Foriginal%3Fcontent-type%3Dapplication%252Fzip%26name%3DREAscreen_IO_CRC.zip&data=05%7C02%7Cjulien.mortier%40vib.be%7C1a45432012054bce911908dd832ecb2f%7C2d714a65b97f41a98ff1ec2cdf7df5cd%7C0%7C0%7C638810959196608917%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=gNnFXb05qxfzDd0luMLpLHKoHNi27pgZ9VU8RpNiMJs%3D&reserved=0

Parameters:

• subset (bool (default: True)) – Whether to load a pre-defined subset of the dataset (5-plex). Set to False to load the full dataset (63-plex, ~50 GB).

• path (str | Path | None (default: None)) – If None, the example data will be downloaded into the default cache directory for your OS. Provide a custom path to change this behavior.

• **kwargs – Additional keyword arguments passed to harpy.io.macsima().

Return type:

SpatialData

Returns:

: A spatialdata.SpatialData object containing the MACSima colorectal carcinoma imaging data.

See also

harpy.io.macsima

Reader for MACSima data.